(DOWNLOAD) "Precursor Lymphoblastic Lymphoma Reoccurring As a Donor-Derived Neoplasm: A Case Report and Review of the Literature (Case Reports) (Report)" by Archives of Pathology & Laboratory Medicine ~ eBook PDF Kindle ePub Free
eBook details
- Title: Precursor Lymphoblastic Lymphoma Reoccurring As a Donor-Derived Neoplasm: A Case Report and Review of the Literature (Case Reports) (Report)
- Author : Archives of Pathology & Laboratory Medicine
- Release Date : January 01, 2008
- Genre: Health & Fitness,Books,Health, Mind & Body,
- Pages : * pages
- Size : 232 KB
Description
Posttransplant lymphoproliferative disorder (PTLD) encompasses a heterogeneous group of diseases characterized by lymphoid proliferation or lymphoma occurring as a result of immunosuppression in solid organ or bone marrow allograft transplant recipients. (1) Lesions arising less than 1 year posttransplantation are predominantly attributable to genomic integration of Epstein-Barr virus (EBV); by contrast, lesions occurring late after transplantation represent a distinct entity that is unassociated with EBV. (2,3) Precursor T lymphoblastic lymphoma (T-LBL) comprises the majority of lymphoblastic lymphomas, with most occurring in adolescent males. (4) The pathogenesis of these neoplasms remains unknown, and several molecular attributes have been described. Lesions are characterized by T lymphoblasts with medium-sized cells, scant cytoplasm, and variable prominence of nucleoli. (4)
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